Information for Dog Owners

What is regenerative medicine?
The aim of regenerative medicine is to replace or regenerate tissues or organs that have been damaged by disease, trauma, or congenital condition and as such differs from current clinical strategies that focus mainly on the treatment of symptoms. Regenerative medicine employs techniques that stimulate the organism’s own repair mechanisms to heal and restore lost functions.
Dysplasia, which affects mostly medium and large dogs, leads to irreversible damage to the joints and osteoarthritis (cartilage wear, bone surface abrasion). The result is chronic pain, lameness, and a permanent decline in the quality of life. The current treatments used by veterinarians are generally confined to surgery, anti-inflammatory and analgesic drugs, cartilage-fortifying supplements and physiotherapy.
The administration of mesenchymal stem cells (MSCs), however, may provide a new and permanent solution. Our method isolates MSCs from orthopedically healthy dogs and injects them locally into the joint of the sick dog, achieving a long symptom-free period or even full recovery. To date, our veterinary partners have treated more than 100 cases of moderate or severe osteoarthritis in dogs employing this minimally-invasive, single dose MSC transplantation in research trial settings. After this therapy, lameness due to cartilage wear was significantly reduced for a long period, even after one year.

Why are we developing stem-cell treatment? Because

it is non-invasive, a single injection is effective. it reduces discomfort and, potentially, pain relievers can be discontinued. it prevents disease progression and enhances reversal. only these cells are capable of regenerating damaged cartilage; no other procedure is available. its effect is long lasting.